Nestlé has launched a new line of protein-based drinks aimed at supporting people on weight loss journeys, particularly those using GLP-1 medications such as Ozempic. The products, developed using a proprietary whey protein microgel technology, are designed to help regulate appetite, stabilise blood sugar and preserve muscle mass.

The innovation is part of Nestlé’s strategic focus on weight management and personalised nutrition. Its scientists have filed over 100 patents for whey protein innovations in the past decade, including 11 supporting this latest microgel format.

Clinical trial findings

Clinical trials carried out by Nestlé scientists and external partners found that a pre-meal drink containing 10g of the whey protein microgels lowered glucose response and increased levels of GLP-1 — a gut hormone that enhances feelings of fullness and slows digestion. The results of the study were recently published in the journal metabolites.

Christophe Schmitt, Senior Expert Protein Science & Technology at Nestlé Research said:

Whey protein is known for its high nutritional quality but can clump together when heated as a concentrated liquid, an essential step for making shelf-stable ready-to-drink beverages. This can result in increased thickness of the liquid and off flavours. Our novel technology enables us to develop beverages with high concentrations of whey protein, while ensuring great taste and texture for the consumer..”

The first commercial product to use the technology is Boost Pre-Meal Hunger Support, a portable whey protein shot now being tested in selec US shops. It is designed to be consumed 10 to 30 minutes before a meal to stimulate the body’s natural GLP-1 response and reduce appetite.

To further support those using GLP-1 receptor agonists, who may face challenges like nutrient deficiencies and lean muscle loss, Nestlé is launching Boost Advanced, a high-protein shake fortified with nutrients that support digestive health and energy metabolism. Containing 35g of protein per serving, it will be available in the US from June in Rich Chocolate and French Vanilla flavours.

Andrew Franklin, President, Holistic Health, Nestlé Health Science US added:

We are leveraging our nutrition science expertise to support consumers on weight loss journeys, including GLP-1 medication users, with innovative solutions. As we explore complementary support to weight loss management, we aim to address arising nutritional needs like maintaining muscle mass and supporting metabolic health with innovations that come in convenient on-the-go formats.”

Addressing side effects of GLP-1 medications

While GLP-1 receptor agonists have shown remarkable results for weight loss, they can also come with unintended nutritional consequences. These medications often reduce overall food intake, which can lead to deficiencies in essential nutrients such as protein, vitamins B12 and D and iron. In some cases, rapid weight loss can also result in the loss of lean muscle mass, rather than just fat, due to low food intake and poor diet quality. This makes muscle maintenance and balanced nutrition crucial for users.

Nestlé’s focus on high-protein, nutrient-enriched drinks directly addresses these concerns, offering products that help maintain muscle while supporting metabolic and digestive health. By integrating scientific research with practical, accessible formats, the company is providing tailored nutritional support that meets the evolving needs of both consumers and healthcare professionals.

Also in development is Full Factor, a ready-to-drink offering under Nestlé’s Vital Pursuit range. Currently undergoing shop testing in the US, the drink contains 15g of protein, 10g of fibre, essential vitamins and no added sugar, aiming to keep consumers feeling fuller for longer.

As GLP-1 medications continue to rise in popularity, Nestlé’s latest innovations mark a timely entry into a growing market — bringing nutritional science to the fore for both health-conscious consumers and clinical users alike.