β-Nicotinamide Mononucleotide is play an important role in the production of human cell energy, which is involved in the synthesis of intracellular NAD (nicotinamide adenine dinucleotide, an important coenzyme for cell energy conversion).Niacinamide (nicotinamide) is a derivative of vitamin B3, also known as niacin. NAD+ is a molecule that holds a variety of functions within the body, mainly through facilitation of cell-signaling enzymes called sirtuins. These enzymes are crucial for normal functioning, with SIRT1 (there are 7 sirtuins) being particularly unique. Research has shown it to be highly active following caloric restriction, which itself brings multiple benefits, including signs of an extending lifespan. Sure enough, further tests have revealed that elevated levels of SIRT1 can lead to protection from metabolic decline and disease.​​

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Is NMN safe and reliable for long-term use?                     

β-Nicotinamide Mononucleotide is a naturally occurring substance found in the human body. It is also found in many foods and is completely natural and harmless.Studies have shown that supplementation of NMN does not affect the activity of various enzymes in the complementary synthesis pathway, Oral NMN has no effect on the activity of NAMPT, PARP, NMNAT and other enzymes in the synthetic pathway, and directly changes the level of NAD+ in our body.

Some common NMN rich foods are listed in CELL magazine as follows:

The research shows that the old people over 65 years old with 70 kg should be supplemented with about 600 mg of NMN every day, and the young people around 45 years old should be supplemented with about 300 mg. This is equivalent to eating about 32kg of green pea or 54kg of broccoli every day, and ensuring complete absorption. It's clear that is not possible at all, so it is particularly important to supplement NMN from non-food sources.


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