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Ornithineis an amino acid that plays a role in the ureacycle. Ornithine is abnormally accumulated in the body in ornithinetranscarbamylase deficiency.
L-Ornithine supplementation attenuatedfatigue in subjects in a placebo-controlled study using a cycle ergometer. Theresults suggested that L-ornithine has an antifatigue effect in increasing theefficiency of energy consumption and promoting the excretion of ammonia.
L-Ornithine L-aspartate (LOLA), a stablesalt of ornithine and aspartic acid, has been used in the treatment ofcirrhosis.
Amino acidsupplements, including L-ornithine, are frequently marketed to bodybuilders andweightlifters through the claim that it will increase levels of human growthhormone (HGH). However, clinical study has shown that these supplements do notincrease levels of HGH with low dose (2 grams per day divided into two doses)supplementation.
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